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Appl Biochem Biotechnol. 2008 Oct;151(1):1-8. doi: 10.1007/s12010-008-8158-7. Epub 2008 Feb 20.

Bacillus phytases: present scenario and future perspectives.

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  • 1College of Animal Science, Zhejiang University, Hangzhou, 310029, People's Republic China.


Phytases are a special class of phosphatases that catalyze the sequential hydrolysis of phytate to less-phosphorylated myo-inositol derivatives and inorganic phosphate. Bacillus phytases, which exhibit their desirable activity profile under neutral pH, higher thermal stability, and strict substrate specificity for the calcium-phytate complex, have considerable potential in commercial and environmental applications. This review describes recent findings concerning the production, biochemical properties, molecular characteristics, and expression of Bacillus phytases. Several potential applications of the Bacillus phytases in animal nutrition, human health, and synthesis of lower myo-inositol phosphates are also summarized.

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