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Ann Behav Med. 2008 Oct;36(2):176-85. doi: 10.1007/s12160-008-9056-5. Epub 2008 Sep 11.

History of unemployment predicts future elevations in C-reactive protein among male participants in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.

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1
Department of Psychology, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA. djanicki@andrew.cmu.edu

Abstract

BACKGROUND:

Unemployment is associated with risk of future morbidity and premature mortality.

PURPOSE:

To examine whether unemployment history predicts future C-reactive protein (CRP) levels in male participants in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.

METHODS:

Unemployment, body mass index (BMI), and health behaviors were measured at 7, 10, and 15 years post-recruitment. CRP was measured at Years 7 and 15.

RESULTS:

Having a history of unemployment at Year 10 was associated with higher CRP at Year 15, independent of age, race, BMI, Year 7 CRP, Year 15 unemployment, and average income across Years 10-15. Poor health practices and depressive symptoms explained 22% of the association, but Year 10 unemployment history remained a significant predictor. Findings did not differ across age, race, education, or income.

CONCLUSIONS:

Discrete episodes of unemployment may have long-term implications for future CRP levels.

PMID:
18784972
DOI:
10.1007/s12160-008-9056-5
[Indexed for MEDLINE]
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