Format

Send to

Choose Destination
Trends Microbiol. 2008 Oct;16(10):480-7. doi: 10.1016/j.tim.2008.07.003. Epub 2008 Sep 4.

The three adaptation systems of Bacillus subtilis chemotaxis.

Author information

1
Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. cvrao@uiuc.edu

Abstract

Adaptation has a crucial role in the gradient-sensing mechanism that underlies bacterial chemotaxis. The Escherichia coli chemotaxis pathway uses a single adaptation system involving reversible receptor methylation. In Bacillus subtilis, the chemotaxis pathway seems to use three adaptation systems. One involves reversible receptor methylation, although quite differently than in E. coli. The other two involve CheC, CheD and CheV, which are chemotaxis proteins not found in E. coli. Remarkably, no one system is absolutely required for adaptation or is independently capable of generating adaptation. In this review, we discuss these three novel adaptation systems in B. subtilis and propose a model for their integration.

PMID:
18774298
PMCID:
PMC3532902
DOI:
10.1016/j.tim.2008.07.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center