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J Biol. 2008 Aug 28;7(6):22. doi: 10.1186/jbiol83.

Evolution of virulence in malaria.

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1
Department of Zoology, University of Oxford, Oxford, OX1 3PS, UK.

Abstract

The pathogenesis of severe malarial disease is not yet fully understood. It is clear that host immunopathology plays a central role, and a recent paper in BMC Evolutionary Biology suggests that the ability of the parasite to stimulate interleukin-10 production is a major factor and speculates on its impact on the coevolution of host and parasite.

PMID:
18771591
PMCID:
PMC2776394
DOI:
10.1186/jbiol83
[Indexed for MEDLINE]
Free PMC Article
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