Format

Send to

Choose Destination
Protein J. 2008 Sep;27(6):371-5. doi: 10.1007/s10930-008-9146-z.

Isolation and characterization of low-molecular-weight chromium-binding substance (LMWCr) from chicken liver.

Author information

1
Department of Chemistry, Georgia Southern University, Statesboro, GA 30460-8064, USA.

Abstract

Chromodulin (also known as low-molecular-weight chromium-binding substance, LMWCr) is a chromium-binding oligopeptide proposed to play a role in insulin signaling and chromium transport in mammals. This laboratory has isolated and purified this material from a non-mammalian source, an avian. Spectroscopic and physical characterization of the isolated material suggests the material is an oligopeptide with a multinuclear chromium assembly bridged via asparatate and glutamate residues very similar to its mammalian counterparts. The isolated material also possesses a biological activity similar to other LMWCr isolates.

PMID:
18769887
DOI:
10.1007/s10930-008-9146-z
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center