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Br J Cancer. 2008 Oct 7;99(7):1161-4. doi: 10.1038/sj.bjc.6604639. Epub 2008 Sep 2.

Maternal, prenatal and perinatal characteristics and first trimester maternal serum hormone concentrations.

Author information

1
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, 6120 Executive Boulevard, Rockville, MD 20892-7246, USA. troisir@mail.nih.gov

Abstract

In uncomplicated pregnancies, first trimester androgen, oestrogen and prolactin concentrations were higher in nulliparous (n=160) than parous (n=260) mothers. Androgens and estrogens were higher in younger than older mothers. These data are consistent with elevated hormone concentrations mediating the breast cancer protection from a first pregnancy and pregnancies occurring at younger ages.

PMID:
18766187
PMCID:
PMC2567091
DOI:
10.1038/sj.bjc.6604639
[Indexed for MEDLINE]
Free PMC Article

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