Metal-triggered radial self-assembly of collagen peptide fibers

J Am Chem Soc. 2008 Sep 24;130(38):12610-1. doi: 10.1021/ja804942w. Epub 2008 Sep 3.

Abstract

A metal-triggered self-assembling collagen peptide was designed and synthesized to generate fibers through a radial growth mechanism. The assembly of the fibers was made possible through the placement of a bipyridine ligands within the center of the triple helix and was triggered by the addition of Fe(II).

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • 2,2'-Dipyridyl / chemistry
  • Circular Dichroism
  • Collagen / chemical synthesis
  • Collagen / chemistry*
  • Ferric Compounds / chemistry*
  • Glycine / chemistry
  • Hydroxyproline / chemistry
  • Light
  • Models, Molecular
  • Peptides / chemical synthesis
  • Peptides / chemistry*
  • Proline / chemistry
  • Protein Structure, Secondary
  • Scattering, Radiation
  • Spectrophotometry, Ultraviolet

Substances

  • Ferric Compounds
  • Peptides
  • 2,2'-Dipyridyl
  • Collagen
  • Proline
  • Hydroxyproline
  • Glycine