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J Med Case Rep. 2008 Sep 1;2:290. doi: 10.1186/1752-1947-2-290.

Unusual clear cell tumors of the jaws - clinical and histopathological considerations: a case report.

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Maxillo-Facial Surgery, Catholic University Medical School, Rome, Italy.



Clear cell neoplasms of the jaw are very infrequent and a review of the literature reports only isolated cases of metastatic renal clear cell carcinoma of the jaw.


A 68-year-old man presented with an osteolytic lesion of the left hemimandible. The first diagnostic hypothesis was a third molar follicular cyst. Surgical treatment consisted of enucleating the lesion preserving the alveolar nerve and extracting of the retained tooth. Unexpectedly, the lesion presented as a solid.


The authors report a case of a clear cell neoplasm involving the jaw in which histopathological exam presented an indeterminate histology. The histological characteristics of this tumor make it unique in the international literature.

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