Non-coding RNA transcription: turning on neighbours

Nat Cell Biol. 2008 Sep;10(9):1023-4. doi: 10.1038/ncb0908-1023.

Abstract

Even though less than 2% of the mammalian genome encodes proteins, a significant fraction can be transcribed into non-coding RNAs. An elegant study identifies a function for non-coding RNA transcription in activating neighbouring genes.

Publication types

  • Comment

MeSH terms

  • Animals
  • Gene Expression Regulation
  • Genes, Immediate-Early
  • Genome
  • Mice
  • NIH 3T3 Cells
  • Oligonucleotide Array Sequence Analysis
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • RNA, Untranslated / genetics*
  • Saccharomyces cerevisiae / genetics
  • Transcription, Genetic*

Substances

  • RNA, Messenger
  • RNA, Untranslated