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Infect Dis Clin North Am. 2008 Sep;22(3):469-88, viii-ix. doi: 10.1016/j.idc.2008.03.010.

Human babesiosis.

Author information

1
Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Boston, MA 02111, USA.

Abstract

Human babesiosis is an emerging intraerythrocytic infection caused by protozoal parasites transmitted by ixodid ticks. Babesiosis is endemic in the northeastern and upper midwestern regions of the United States and is found sporadically in other parts of the United States, Europe, Asia, Africa, and South America. Babesial infections range from asymptomatic to severe and occasionally are fatal. Specific laboratory diagnosis of babesial infection is made by morphologic examination of Giemsa-stained blood smears, serology, and amplification of babesial DNA using polymerase chain reaction. The combination of atovaquone and azithromycin is the treatment of choice for mild-to-moderate illness, whereas clindamycin and quinine and exchange transfusion are indicated for severe disease.

PMID:
18755385
PMCID:
PMC3998201
DOI:
10.1016/j.idc.2008.03.010
[Indexed for MEDLINE]
Free PMC Article

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