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Curr Biol. 2008 Aug 26;18(16):R710-3. doi: 10.1016/j.cub.2008.07.037.

HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase.

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  • 1Department of Microbiology and Molecular Medicine, University of Geneva, CH-1211 Geneva 4, Switzerland. jeremy.luban@unige.ch

Abstract

Factors necessary for HIV-1 nuclear import have been sought for many years. Recent reports suggest that TNPO3/Transportin-SR2 binds to HIV-1 integrase and is required for HIV-1 infection of interphase cells.

PMID:
18727908
DOI:
10.1016/j.cub.2008.07.037
[PubMed - indexed for MEDLINE]
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