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Cell. 2008 Aug 22;134(4):572-5. doi: 10.1016/j.cell.2008.08.007.

A tale of too many centrosomes.

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1
BioT Incorporated, Istanbul Technical University, Istanbul 34390, Turkey.

Abstract

Having the correct number of centrosomes is crucial for proper chromosome segregation during cell division and for the prevention of aneuploidy, a hallmark of many cancer cells. Several recent studies (Basto et al., 2008; Kwon et al., 2008; Yang et al., 2008) reveal the importance of mechanisms that protect against the consequences of harboring too many centrosomes.

PMID:
18724931
DOI:
10.1016/j.cell.2008.08.007
[Indexed for MEDLINE]
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