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Injury. 2008 Sep;39 Suppl 3:S43-8. doi: 10.1016/j.injury.2008.05.015. Epub 2008 Aug 19.

Current treatment concepts for neuromas-in-continuity.

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First Department of Orthopaedics, Athens University Medical School, Athens, Greece.


A neuroma-in-continuity is a neuroma that results from failure of the regenerating nerve growth cone to reach peripheral targets. It occurs within an intact nerve in response to internally damaged fascicles, resulting in a distal portion of the nerve that no longer functions properly. Management of neuromas-in-continuity is challenging. Chemical methods, and microsurgical techniques including fascicular ligation, and burying into muscle and bone have been reported to prevent neuroma-in-continuity formation. The purpose of this article is to present novel techniques for neuroma-in-continuity management, and to discuss the related literature.

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