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Clin Transplant. 2008 Nov-Dec;22(6):833-6. doi: 10.1111/j.1399-0012.2008.00874.x. Epub 2008 Aug 18.

A pitfall in screening with decoy cells after simultaneous pancreas kidney transplantation.

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  • 1Departments of Nephrology, Leiden University Medical Center, Leiden, The Netherlands.


In this report, we describe a bladder-drained simultaneous pancreas-kidney transplant (SPKT) recipient with a polyoma virus-associated nephropathy (PVAN) in whom the urine cytology failed to detect decoy cells despite repeated attempts. Several tests were performed to confirm our hypothesis that pancreatic enzymes can degrade decoy cells and granulocytes. This case illustrates an important pitfall in the urinary screening for PVAN with cytology and for urinary tract infections with urine sediment in bladder-drained SPKT recipients.

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