Format

Send to

Choose Destination
J Org Chem. 2008 Sep 19;73(18):7260-5. doi: 10.1021/jo801151x. Epub 2008 Aug 19.

Cobalt-catalyzed asymmetric olefin aziridination with diphenylphosphoryl azide.

Author information

1
Department of Chemistry, University of South Florida, Tampa, Florida 33620-5250, USA.

Abstract

The cobalt(II) complexes of D2-symmetric chiral porphyrins, such as 3,5-Di(t)Bu-ChenPhyrin P5, can catalyze asymmetric olefin aziridination with diphenylphosphoryl azide (DPPA) as a nitrene source. Acceptable asymmetric inductions were observed for the [Co(P5)]-based catalytic system, forming the desired N-phosphorus-substituted aziridines in moderate to high yields and good enantioselectivities.

PMID:
18710285
DOI:
10.1021/jo801151x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center