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Mol Plant Pathol. 2008 Jan;9(1):105-18. doi: 10.1111/j.1364-3703.2007.00438.x.

Mining the genomes of plant pathogenic bacteria: how not to drown in gigabases of sequence.

Author information

1
Department of Plant Pathology, Physiology, and Weed Sciences, Virginia Tech, Blacksburg, VA 24061, USA. vinatzer@vt.edu

Abstract

Hundreds of bacterial genomes including the genomes of dozens of plant pathogenic bacteria have been sequenced. These genomes represent an invaluable resource for molecular plant pathologists. In this review, we describe different approaches that can be used for mining bacterial genome sequences and examples of how some of these approaches have been used to analyse plant pathogen genomes so far. We review how genomes can be mined one by one and how comparative genomics of closely related genomes releases the true power of genomics. Databases and tools useful for genome mining that are publicly accessible on the Internet are also described. Finally, the need for new databases and tools to efficiently mine today's plant pathogen genomes and hundreds more in the near future is discussed.

PMID:
18705888
PMCID:
PMC6640517
DOI:
10.1111/j.1364-3703.2007.00438.x
[Indexed for MEDLINE]
Free PMC Article

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