Format

Send to

Choose Destination
See comment in PubMed Commons below
J Am Chem Soc. 2008 Sep 10;130(36):11836-7. doi: 10.1021/ja801968f. Epub 2008 Aug 13.

Photoswitched DNA-binding of a photochromic spiropyran.

Author information

1
Department of Chemical and Biological Engineering, Physical Chemistry, Chalmers University of Technology, SE-412 96 Göteborg, Sweden.

Abstract

The dramatically different DNA-binding properties of the two isomeric forms of a photochromic spiropyran have been demonstrated, enabling photoswitched DNA binding. The closed, UV-absorbing form shows no signs of interaction with DNA. Upon UV exposure the spiropyran is isomerized to the open form that binds to DNA by intercalation. The process is fully reversible as the corresponding dissociation process is induced by visible light.

PMID:
18698779
DOI:
10.1021/ja801968f
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center