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Biochim Biophys Acta. 2009 Jan;1793(1):20-6. doi: 10.1016/j.bbamcr.2008.07.005. Epub 2008 Jul 21.

The molecular mechanism of mitochondrial fusion.

Author information

1
Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616, USA.

Abstract

This review is focused on mitochondrial membrane fusion, which is a highly conserved process from yeast to human cells. We present observations from both yeast and mammalian cells that have provided insights into the mechanism of mitochondrial fusion and speculate on how the key players, which are dynamin-related GTPases do the work of membrane tethering and fusion.

PMID:
18691613
DOI:
10.1016/j.bbamcr.2008.07.005
[Indexed for MEDLINE]
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