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Mol Biol Evol. 2008 Oct;25(10):2241-6. doi: 10.1093/molbev/msn172. Epub 2008 Aug 9.

Subdivision in an ancestral species creates asymmetry in gene trees.

Author information

1
Department of Integrative Biology, University of California at Berkeley, USA. slatkin@berkeley.edu

Abstract

We consider gene trees in three species for which the species tree is known. We show that population subdivision in ancestral species can lead to asymmetry in the frequencies of the two gene trees not concordant with the species tree and, if subdivision is extreme, cause the one of the nonconcordant gene trees to be more probable than the concordant gene tree. Although published data for the human-chimp-gorilla clade and for three species of Drosophila show asymmetry consistent with our model, sequencing error could also account for observed patterns. We show that substantial levels of persistent ancestral subdivision are needed to account for the observed levels of asymmetry found in these two studies.

PMID:
18689871
PMCID:
PMC2734134
DOI:
10.1093/molbev/msn172
[Indexed for MEDLINE]
Free PMC Article

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