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J Bacteriol. 2008 Oct;190(20):6927-30. doi: 10.1128/JB.00801-08. Epub 2008 Aug 8.

Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa.

Author information

1
Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Abstract

The pvc gene cluster from Pseudomonas aeruginosa has been linked to the biosynthesis of both the pyoverdine chromophore and pseudoverdine. Our reinvestigation of the role this gene cluster plays in P. aeruginosa secondary metabolite biosynthesis shows that its major product is actually paerucumarin, a novel isonitrile functionalized cumarin.

PMID:
18689486
PMCID:
PMC2566218
DOI:
10.1128/JB.00801-08
[Indexed for MEDLINE]
Free PMC Article

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