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Int J Nanomedicine. 2008;3(2):151-67.

Potential clinical applications of quantum dots.

Author information

  • 1Center for Bio/Molecular Science and Engineering, Code 6900, US Naval Research Laboratory,Washington, DC, USA. imedintz@cbmse.nrl.navy.mil

Abstract

The use of luminescent colloidal quantum dots in biological investigations has increased dramatically over the past several years due to their unique size-dependent optical properties and recent advances in biofunctionalization. In this review, we describe the methods for generating high-quality nanocrystals and report on current and potential uses of these versatile materials. Numerous examples are provided in several key areas including cell labeling, biosensing, in vivo imaging, bimodal magnetic-luminescent imaging, and diagnostics. We also explore toxicity issues surrounding these materials and speculate about the future uses of quantum dots in a clinical setting.

PMID:
18686776
PMCID:
PMC2527673
[PubMed - indexed for MEDLINE]
Free PMC Article
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