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Int J Nanomedicine. 2008;3(2):151-67.

Potential clinical applications of quantum dots.

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  • 1Center for Bio/Molecular Science and Engineering, Code 6900, US Naval Research Laboratory,Washington, DC, USA.


The use of luminescent colloidal quantum dots in biological investigations has increased dramatically over the past several years due to their unique size-dependent optical properties and recent advances in biofunctionalization. In this review, we describe the methods for generating high-quality nanocrystals and report on current and potential uses of these versatile materials. Numerous examples are provided in several key areas including cell labeling, biosensing, in vivo imaging, bimodal magnetic-luminescent imaging, and diagnostics. We also explore toxicity issues surrounding these materials and speculate about the future uses of quantum dots in a clinical setting.

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