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Curr Biol. 2008 Aug 5;18(15):R653-R655. doi: 10.1016/j.cub.2008.06.040.

Gene regulation: boundaries within limits.

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1
Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824-1319, USA.

Abstract

Quantitative measurements of the Hunchback transcription factor in Drosophila embryos show that its target genes can respond with a high degree of precision to the exact level of the protein, simulating a continuous, analog readout, while other target genes show a combinatorial effect, resembling a Boolean logic element.

PMID:
18682204
DOI:
10.1016/j.cub.2008.06.040
[Indexed for MEDLINE]
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