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J Clin Rheumatol. 2009 Feb;15(1):25-6. doi: 10.1097/RHU.0b013e31817d1197.

Infiltration of histiocytes and multinucleated giant cells in the myocardium of a patient with multicentric reticulohistiocytosis.

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1
Division of Rheumatology, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

Abstract

Multicentric reticulohistiocytosis (MRH) is a rare multisystem disease characterized by skin nodules and a destructive polyarthritis. We describe cardiac disease in a 42-year-old African American female with a history of MRH for 29 years and dilated cardiomyopathy for 5 years. During a congestive heart failure flare, the patient was slow to respond to standard treatment. A left/right heart catheterization and endomyocardial biopsy were performed, and the patient was found to have evidence of myocardial MRH infiltration.

PMID:
18679136
DOI:
10.1097/RHU.0b013e31817d1197
[Indexed for MEDLINE]
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