Format

Send to

Choose Destination
See comment in PubMed Commons below
Biochim Biophys Acta. 2009 Jan;1793(1):33-41. doi: 10.1016/j.bbamcr.2008.06.021. Epub 2008 Jul 12.

Thirty years of protein translocation into mitochondria: unexpectedly complex and still puzzling.

Author information

1
Institute for Physiological Chemistry, Ludwig-Maximilians University, Butenandtstr. 5, 81377 Munich, Germany.

Abstract

Mitochondria are essential organelles of the eukaryotic cells that are made by expansion and division of pre-existing mitochondria. The majority of their protein constituents are synthesized in the cytosol. They are transported into and put together within the organelle. This complex process is facilitated by several protein translocases. Here we summarize current knowledge on these sophisticated molecular machines that mediate recognition, transport across membranes and intramitochondrial sorting of many hundreds of mitochondrial proteins.

PMID:
18672008
DOI:
10.1016/j.bbamcr.2008.06.021
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center