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Science. 2008 Aug 1;321(5889):640. doi: 10.1126/science.1153058.

Comment on "magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain".

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1
Department of Molecular, Microbial, and Structural Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3305, USA. hoch@uchc.edu

Abstract

Manganas et al. (Reports, 9 November 2007, p. 980) used nuclear magnetic resonance spectroscopy to identify a biomarker of neural progenitor cells. However, their analysis relies on spectral processing methods that are known to be problematic. Absent detection using alternate methods of spectrum analysis or controls to quantify the false discovery rate, their conclusions may be premature.

PMID:
18669844
PMCID:
PMC3049173
DOI:
10.1126/science.1153058
[Indexed for MEDLINE]
Free PMC Article
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