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Am J Obstet Gynecol. 2008 Dec;199(6):639.e1-4. doi: 10.1016/j.ajog.2008.05.026. Epub 2008 Jul 29.

In utero fetal oximetry via visible light spectroscopy in twin-twin transfusion syndrome.

Author information

1
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL, USA.

Abstract

OBJECTIVE:

The purpose of this study was to assess fetal tissue venous oxygenation (StO2%) in utero during laser therapy for twin-twin transfusion syndrome via visible light spectroscopy (VLS).

STUDY DESIGN:

StO2% was measured in 10 donor and recipient twins at the level of the skin and placenta before and after laser therapy (SLPCV).

RESULTS:

Pre-SLPCV skin StO2% was significantly lower in the donor than in the recipient twin (21.6 +/- 6.2 vs 31.2 +/- 8.6, respectively; P = .01), but the difference disappeared after SLPCV. Placental surface StO2% measurements in 5 patients showed a significant increase in StO2% in the territory of the recipient (P = .04). Preoperative linear streaming as evidence of nonadmixing deoxygenated and oxygenated blood disappeared after SLPCV.

CONCLUSION:

In utero StO2% measurement is possible with VLS. Donor twins can have significantly less StO2% than recipient twins, but this is corrected after SLPCV. Further studies are warranted to determine the value of in utero VLS oximetry.

PMID:
18667174
DOI:
10.1016/j.ajog.2008.05.026
[Indexed for MEDLINE]

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