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Parasitology. 1991 Jun;102 Pt 3:367-70.

Characterization of the lipid content of Toxoplasma gondii rhoptries.

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Laboratoire de Biochimie M├ędicale, Angers, France.


Quantitative and qualitative analysis of lipids has been performed on a rhoptry fraction purified from Toxoplasma gondii tachyzoites. The lipid to protein ratio was estimated to be 0.26. The cholesterol to phospholipid ratio was unusually high at 1.48. Phosphatidylcholine was the major phospholipid; phosphatidylserine, phosphatidylinositol and sphingomyelin were absent whereas significant amounts of phosphatidic acid and lysophospholipids were found. This pelicular composition could be related to functional involvement of the organelle in host-cell invasion.

[Indexed for MEDLINE]

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