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Diagn Pathol. 2008 Jul 25;3:31. doi: 10.1186/1746-1596-3-31.

Histological variants of cutaneous Kaposi sarcoma.

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Histopathology Department, Ampath National Laboratory Support Services, Johannesburg, South Africa.


This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS. Involuting lesions as a result of treatment related regression are also presented.

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