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J Antibiot (Tokyo). 2008 May;61(5):326-9. doi: 10.1038/ja.2008.47.

Stawamycin analog, JBIR-11 from Streptomyces viridochromogenes subsp. sulfomycini NBRC 13830.

Author information

1
Japan Biological Information Research Center (JBIRC), Japan Biological Informatics Consortium (JBIC), Aomi, Tokyo, Japan.

Abstract

A stawamycin analog, JBIR-11 (1) was isolated from mycelium of Streptomyces viridochromogenes subsp. sulfomycini NBRC 13830. The structure was determined on the basis of the spectroscopic data. Compound 1 exhibited growth inhibitory effect against human fibrosarcoma HT1080 cells with an IC50 value of 25 microM.

PMID:
18654000
DOI:
10.1038/ja.2008.47
[Indexed for MEDLINE]

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