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Zhongguo Zhong Yao Za Zhi. 2008 May;33(9):1075-7.

[Sdudy on effect of tripterygium on plasma IL-18 content in patients with lupus nephritis].

[Article in Chinese]

Author information

1
Department of dermatology, School of Medicine, Taizhou College, Taizhou 318000, China.

Abstract

OBJECTIVE:

It is to study the effect of tripterygium (TW) on the plasma IL-18 content in patients with lupus nephritis (LN) and its treatment value.

METHOD:

The patients with LN treated with prednisone were divided into active groupand inactive group with active index. The active group was given tripterygium additionally. The changing of plasma IL-18 and release of nephritis were observed after treatment for three months.

RESULT:

The level of plasma IL-18 lowered down obviously, urinary protein decreased, LN activity index, hematuria and renal function improved.

CONCLUSION:

Tripterygium caninhibitroduction of plasma IL-18. It has definite treatment value on controlling LN activity.

PMID:
18652362
[Indexed for MEDLINE]

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