Format

Send to

Choose Destination
Drug Dev Ind Pharm. 2008 Dec;34(12):1388-93. doi: 10.1080/03639040802130053 .

Antifungal activity of the essential oil of Thymus vulgaris L. and thymol on experimentally induced dermatomycoses.

Author information

1
Institute for Biological Research, S. Stankovic, Bulevar despota Stefana, Belgrade, Serbia. mris@ibiss.bg.ac.yu

Abstract

The in vivo evaluation of the toxicological and antifungal activity of the essential oil of Thymus vulgaris L. and its main component thymol was made on 2-month-old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats, using the most frequent dermatomycetes, Trichophyton mentagrophytes, T. rubrum, and T. tonsurans. The therapeutic efficacy of a 1% solution of the essential oil of Thymus vulgaris and thymol as well as the commercial preparation bifonazole was evaluated. During the 37-day observation period the oil-treated animals were cured.

PMID:
18651285
DOI:
10.1080/03639040802130053
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center