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J Am Acad Dermatol. 2008 Sep;59(3):518-23. doi: 10.1016/j.jaad.2008.05.011. Epub 2008 Jul 21.

Molecular diagnosis of a benign proliferative nodule developing in a congenital melanocytic nevus in a 3-month-old infant.

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1
Division of Dermatopathology, University of Connecticut School of Medicine, Farmington, Connecticut 06030, USA. drmichaelmurphy@netscape.net

Abstract

Small and intermediate congenital melanocytic nevi have a lifetime risk of developing melanoma estimated to range from 0% to 5%. Secondary benign melanocytic proliferations commonly arise in congenital melanocytic nevi; however, some are difficult to definitively distinguish from malignant melanoma based on clinical features and conventional histology. Herein, we describe the use of comparative genomic hybridization in supporting the diagnosis of a deep penetrating nevus developing within a congenital melanocytic nevus of a 3-month-old infant.

PMID:
18640742
DOI:
10.1016/j.jaad.2008.05.011
[Indexed for MEDLINE]
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