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Antimicrob Agents Chemother. 2008 Sep;52(9):3433-7. doi: 10.1128/AAC.01534-07. Epub 2008 Jul 14.

Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.

Author information

1
Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.

Abstract

We report here a comparative study of the anti-hepatitis C virus (HCV) activities of selected (i) nucleoside polymerase, (ii) nonnucleoside polymerase, (iii) alpha,gamma-diketo acid polymerase, (iv) NS3 protease, and (v) helicase inhibitors, as well as (vi) cyclophilin binding molecules and (vii) alpha 2b interferon in four different HCV genotype 1b replicon systems.

PMID:
18625766
PMCID:
PMC2533444
DOI:
10.1128/AAC.01534-07
[Indexed for MEDLINE]
Free PMC Article

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