Send to

Choose Destination
Diagn Microbiol Infect Dis. 2008 Sep;62(1):110-2. doi: 10.1016/j.diagmicrobio.2008.05.010. Epub 2008 Jul 11.

Zabofloxacin (DW-224a) activity against Neisseria gonorrhoeae including quinolone-resistant strains.

Author information

JMI Laboratories, North Liberty, IA 52317, USA.


Zabofloxacin, a new fluoroquinolone compound (DW-224a), was tested by reference agar dilution methods against 35 strains of multiresistant Neisseria gonorrhoeae. The potency of zabofloxacin (MIC(50), 0.016 microg/mL) was generally comparable with azithromycin but 8-fold superior to ciprofloxacin. This novel naphthyridine should be explored as an alternative therapy for quinolone-nonsusceptible gonorrhea and Chlamydia trachomatis infections.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center