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J Nutr Health Aging. 2008 Aug-Sep;12(7):433-50.

Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives.

Author information

1
Inserm U558, F-31073Toulouse, France. rolland.y@chu-toulouse.fr

Abstract

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.

PMID:
18615225
PMCID:
PMC3988678
[Indexed for MEDLINE]
Free PMC Article

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