Send to

Choose Destination
See comment in PubMed Commons below
Int J Antimicrob Agents. 1997 May;8(4):253-6.

HPLC residues of enrofloxacin and ciprofloxacin in eggs of laying hens.

Author information

Farmacologia-Dpto. de Clinica Animal, Facultad de Agronomia y Veterinaria, Universidad Nacional de Rio Cuarto, Ruta 36, km 601, 5800-Rio Cuarto (Cba), Argentina.


Eggs of 12 laying hens with 5 mg/kg/day oral administration of 5% enrofloxacin (EFX) or ciprofloxacin (CFX) solution during 5 days contained residues from 0.02 to 1.98 microg/g (EFX) or 0.14 to 0.28 microg/g (CFX). At identical dosage regime High Performance Liquid Chromatograhy (HPLC) residues of EFX were 6-fold greater than CFX ones. Maximun concentrations were detected at the second day after the administration withdrawal. The limits of detection were 0.019 microg/g for EFX and 0.156 microg/g for CFX. The recovery was 36-50% for CFX and 49-85% for EFX. The withdrawal treatment periods in hens are six days for EFX and five days for CFX in order to avoid violative levels of egg residues.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center