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Cancer Imaging. 2008 Jun 30;8:135-45. doi: 10.1102/1470-7330.2008.0020.

The effect of tamoxifen on the genital tract.

Author information

1
Department of Radiology, Georgetown University Hospital, 3800 Reservoir Road, Washington, DC 20007, USA. sandrapolin@gmail.com

Abstract

Tamoxifen is a selective estrogen receptor modulator (SERM) that is widely used in the treatment of patients with breast cancer and for chemoprophylaxis in high risk women. Tamoxifen results in a spectrum of abnormalities involving the genital tract, the most significant being an increased incidence of endometrial cancer and uterine sarcoma. This article reviews the effects of tamoxifen on the genital tract and the strengths and weaknesses of various imaging modalities for evaluating the endometrium.

PMID:
18603495
PMCID:
PMC2482152
DOI:
10.1102/1470-7330.2008.0020
[Indexed for MEDLINE]
Free PMC Article

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