Format

Send to

Choose Destination
Biol Psychol. 2008 Oct;79(2):239-42. doi: 10.1016/j.biopsycho.2008.06.002. Epub 2008 Jun 14.

Fine-mapping at the HTR2A locus reveals multiple episodic memory-related variants.

Author information

1
Division of Molecular Psychology, University of Basel, Basel, Switzerland. jessica.sigmund@unibas.ch

Abstract

A functional polymorphism (His452Tyr) in the gene encoding the serotonin 2A receptor (HTR2A) has been previously associated with human episodic memory performance and with differences in brain volume in memory-related brain regions. Here we present data obtained through imputation and fine-mapping showing that multiple loci within HTR2A are significantly associated with human memory performance independently of the His452Tyr polymorphism. Our data support the existence of multiple memory-related loci within HTR2A.

PMID:
18602445
DOI:
10.1016/j.biopsycho.2008.06.002
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center