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Pediatr Infect Dis J. 2008 Aug;27(8):765-7. doi: 10.1097/INF.0b013e31816fc34c.

Empiric antibiotic therapy for acute osteoarticular infections with suspected methicillin-resistant Staphylococcus aureus or Kingella.

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1
Department of Pediatrics, Arrowhead Regional Medical Center, Colton, CA, USA.

Abstract

The bacterial agents causing bone and joint infections have been changing. Currently, methicillin-resistant Staphylococcus aureus (MRSA) and Kingella kingae are emerging pathogens. For treatment of MRSA infections, clindamycin, vancomycin, and linezolid are commonly prescribed antibiotics. Kingella are sensitive to most penicillins and cephalosporins. Because MRSA osteoarticular infections tend to be severe, longer periods of antibiotic treatment with more frequent monitoring of inflammatory markers are sometimes required to obtain a complete cure with no residual complications. To assist management, we have included a clinical decision tree with antibiotic treatment protocols.

PMID:
18600193
DOI:
10.1097/INF.0b013e31816fc34c
[Indexed for MEDLINE]
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