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[Applications of metabonomics in clinical diagnosis].

[Article in Chinese]

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1
Modern Research Center for Traditional Chinese Medicine, School of Pharmacy, Second Military Medical University, Shanghai 200433, China.

Abstract

Metabonomics, as a newly developed technique, is expected to be a powerful technique in clinical diagnosis. Metabonomics-based diagnosis involves the global metabolic analysis of body-fluids, determination of biomarkers by multivariate statistic analysis, and establishemen of mathematic models for clinical diagnosis with the aid of pattern recognition. This article reviews the adoption of various analytical and computational strategies, application of metabonomics in clinical diagnosis, and potential challenges and development trends.

PMID:
18595264
[Indexed for MEDLINE]
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