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J Vasc Interv Radiol. 2008 Jul;19(7):1018-26. doi: 10.1016/j.jvir.2008.03.006. Epub 2008 Apr 28.

Effectiveness of a new tunneled catheter in preventing catheter malfunction: a comparative study.

Author information

1
Division of Vascular Surgery, Department of Surgery, Henry Ford Hospital, 2799 W Grand Boulevard, Detroit, MI 48202, USA.

Abstract

PURPOSE:

To compare infection and malfunction rates of two different types of antimicrobial-eluting tunneled cuffed catheters (TCCs) for hemodialysis.

MATERIALS AND METHODS:

The HemoSplit TCC with BioBloc (silver sulfadiazine) coating (n = 100, control group) and the Tal Palindrome Ruby TCC, which has a novel silver antimicrobial sleeve and a spiral-z tip design (n = 100, study group), were compared in this case-controlled study. The main endpoints were TCC infection and malfunction.

RESULTS:

Primary-assisted TCC patency was significantly reduced with the BioBloc TCC (71% and 61% at 90 and 180 days, respectively) compared with the Palindrome Ruby TCC (94% at 90 and 180 days, P < .0001). Multivariate analysis identified only the BioBloc TCC and common femoral access site as independent predictors of worse patency. The unadjusted relative risk (95% confidence interval) for TCC dysfunction with the BioBloc compared with the Palindrome Ruby was 6.0 (2.33-15.53, P < .001), and the relative risk adjusted for access site was 3.2 (1.71-11.96, P = .002). The infection-free rates of the two TCC types were similar (P = .36). The reintervention-free rate for infection or malfunction was significantly better with the Palindrome Ruby TCC (76% and 58% at 90 and 180 days, respectively) than with the BioBloc TCC (60% and 45% at 90 and 180 days, respectively; P = .03).

CONCLUSIONS:

The results support the use of the Palindrome Ruby TCC on the basis of the significantly lower thrombosis and reintervention rate; randomized trials are justified to confirm this finding and to evaluate its role in the prevention of TCC infection.

PMID:
18589315
DOI:
10.1016/j.jvir.2008.03.006
[Indexed for MEDLINE]

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