Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Med. 2008 Jul;121(7):555-61. doi: 10.1016/j.amjmed.2008.02.036.

Update on fibromyalgia therapy.

Author information

1
Division of Rheumatology, Department of Medicine, The University of Connecticut School of Medicine, Farmington, USA. aabeles@uchc.edu

Abstract

Primary fibromyalgia, a poorly-understood chronic pain syndrome, is characterized by widespread musculoskeletal pain, nonrestorative sleep, fatigue, psychological distress, and specific regions of localized tenderness, all in the absence of otherwise apparent organic disease. While the etiology of fibromyalgia is unclear, accumulating data suggest that disordered central pain processing likely plays a role in the pathogenesis of symptoms. Although various pharmacological treatments have been studied and espoused for treating fibromyalgia, no single drug or group of drugs has proved to be particularly useful in treating fibromyalgia patients as a whole, and only one drug to date has earned U.S. Food and Drug Administration approval for treating the syndrome in the United States. This review critically and systematically evaluates clinical investigations of medicinal and nonmedicinal treatments for fibromyalgia dating from 1970 to 2007.

PMID:
18589048
DOI:
10.1016/j.amjmed.2008.02.036
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center