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Eur J Radiol. 2008 Dec;68(3 Suppl):S13-7. doi: 10.1016/j.ejrad.2008.04.031. Epub 2008 Jun 30.

X-ray phase radiography and tomography of soft tissue using grating interferometry.

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  • 1European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble, France.


X-ray phase and absorption radiographs and tomograms of the heart of a rat were taken with an X-ray grating interferometer with monochromatic synchrotron radiation at a photon energy of 17.5 keV. The phase images show largely superior quality with respect to the absorption images taken with the same dose, particularly much better contrast and contrast-to-noise ratio. Different tissues can clearly be distinguished. The results demonstrate the potential of grating interferometry for two- and three-dimensional X-ray imaging of biological soft tissue in an aqueous environment.

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