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Anaesthesia. 2008 Jul;63(7):764-6. doi: 10.1111/j.1365-2044.2008.05482.x.

Panton-Valentine Leukocidin associated with community acquired methicillin resistant Staphylococcus aureus: a case report and review of interim guidelines.

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Department of Anaesthetics, Kent and Sussex Hospital, Mount Ephraim, Tunbridge Wells, Kent TN4 9JG, UK.


We report a case of community acquired methicillin resistant Staphylococcus aureus pneumonia. The causative organism was positive for the toxin Panton-Valentine Leukocidin. This resulted in a severe pneumonia requiring a prolonged stay on our intensive care unit. This infection is becoming more common in the United Kingdom. It can cause a far more aggressive illness than the hospital acquired infection with a high mortality if it becomes an invasive infection. The Department of Health has recently produced interim guidelines for its treatment which we have also reviewed.

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