Send to

Choose Destination
See comment in PubMed Commons below
Adv Anat Pathol. 2008 Jul;15(4):211-7. doi: 10.1097/PAP.0b013e31817bf596.

Identifying cross contaminants and specimen mix-ups in surgical pathology.

Author information

  • 1Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA.


Maintaining patient identity throughout laboratory processing is critical for any diagnostic pathology laboratory. It has also been listed as a main National Patient Safety Goal for the Joint Commission Laboratory Goals. Most pathology facilities have excellent quality assurance programs and initiatives that include multiple checkpoints to ensure that specimen identity is carefully maintained. Even in the best laboratory operations, however, the potential for specimen mix-up, cross contamination, floaters, or carry-over artifacts cannot be eliminated completely. The work-up and analysis of these cases can be challenging to the pathologist for a number of reasons, including the fact that there is no standardized approach. This review discusses a standardized approach that includes clinical correlation, laboratory correlation, and laboratory analysis, potentially including a molecular DNA fingerprinting analysis. The methods and techniques behind DNA fingerprinting for tissue and sample identity are also discussed in detail.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Support Center