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J Dent Res. 2008 Jul;87(7):687-91.

Extracorporeal shock wave therapy induces alveolar bone regeneration.

Author information

1
Department of Periodontology, College of Dentistry, D11-24, University of Florida, Gainesville, FL 32610, USA.

Abstract

Periodontal inflammation with alveolar bone resorption is a hallmark of periodontitis. We hypothesized that extracorporeal shock wave therapy (ESWT) could promote the regeneration of alveolar bone following Porphyromonas gingivalis-induced periodontitis in rats. Rats were infected with P. gingivalis for 10 wks, which caused alveolar bone resorption. The rats were then treated with a single episode of 100, 300, or 1000 impulses of shock wave on both cheeks at energy levels 0.1 mJ/mm(2). Alveolar bone levels were determined at 0, 3, 6, and 12 wks following ESWT and compared with those in untreated controls. Infected rats treated with 300 and 1000 impulses demonstrated significantly improved alveolar bone levels at 3 wks compared with untreated controls, and the improved levels remained for at least 6 wks in most rats. The results demonstrated effective regeneration of alveolar bone by ESWT and suggested that ESWT should be evaluated as an adjunct in the regeneration of periodontal tissues following periodontal disease.

ABBREVIATIONS:

ESWT, extracorporeal shock wave therapy; PCR, polymerase chain-reaction.

PMID:
18573992
DOI:
10.1177/154405910808700703
[Indexed for MEDLINE]

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