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Fertil Steril. 2009 Jun;91(6):2376-80. doi: 10.1016/j.fertnstert.2008.03.060. Epub 2008 Jun 20.

Occurrence of Mycoplasma genitalium in fertile and infertile women.

Author information

1
Gynecology Clinic, 2nd Department of Gynecology and Obstetrics, Wroclaw Medical University, Wrocław, Poland. joannagrzesko@gmail.com

Abstract

OBJECTIVE:

To determine the frequency of occurrence of Mycoplasma genitalium in the reproductive organs of infertile women in comparison with a control group of healthy, fertile women.

DESIGN:

Prospective study.

SETTING:

Gynecology Clinic at the 2nd Department of Gynecology and Obstetrics of the Wroclaw Medical University, Poland.

PATIENT(S):

The study included 51 patients with primary infertility (24 women with idiopathic infertility) and 23 women with proven fertility.

INTERVENTION(S):

Cervical smear and smear from the peritoneal cavity, performed during laparoscopy.

MAIN OUTCOME MEASURE(S):

Presence of the genetic material of M. genitalium in the collected material analyzed using polymerase chain reaction (PCR).

RESULT(S):

M. genitalium was found in the cervical canal of 19.6% of all infertile patients and in 4.4% of fertile patients. In addition, the pathogen was discovered in the cervical canal of 29% patients with unexplained (idiopathic) infertility, which in comparison with the fertile group was a statistically significant difference. In the abdominal cavity, M. genitalium was found in 5.8% of patients from the infertile group (in 8.4% patients with idiopathic infertility), whereas it was not detected in the material obtained from the studied fertile patients.

CONCLUSION(S):

The results obtained may suggest that M. genitalium is a species having an impact on impaired fertility in women.

[Indexed for MEDLINE]

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