By statistic analysis interaction of depression and cholesterol level were revealed in such condition r=0.6498. p<0.001. Correlation between personal anxiety and cholesterol level were revealed r=0.4867, p<0.001. Correlation between reactive anxiety and cholesterol level were revealed r=0.7971, p<0.001. These results may have important implications in explaining the pathophysiological mechanisms linking depression and anxiety to cardiovascular disease.