Send to

Choose Destination
See comment in PubMed Commons below
Curr Opin Pharmacol. 2008 Oct;8(5):593-7. doi: 10.1016/j.coph.2008.04.010. Epub 2008 Jun 12.

New strategies for Helicobacter pylori eradication.

Author information

Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.


Helicobacter pylori infection is highly prevalent worldwide and is a major cause of diseases occurring in the upper gastrointestinal tract. Successful eradication therapy improves H. pylori-related symptoms in functional dyspepsia, cures peptic ulcer disease and may prevent gastric cancer. During the past decade, the success rate of recommended eradication regimens declined from over 90% to about 80%, a critical threshold for effectiveness of the therapy according to the current guidelines. This is mainly because of the rising antimicrobial resistance and underlines that it is imperative to develop new treatment approaches. The prevention of the initial infection by a suitable vaccination might be the new therapeutic strategy for the future.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center