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Cytogenet Cell Genet. 1991;57(1):30-2.

Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter----q15.

Author information

1
Department of Molecular Biology, Keio University School of Medicine, Tokyo, Japan.

Abstract

Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p- (6pter----q15::16q24----qter). The gene (BPA230) was located to the chromosome region 6pter----q15.

PMID:
1855390
DOI:
10.1159/000133108
[Indexed for MEDLINE]

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